乙二醇二甲醚沸点
: 二乙二醇二甲醚的英文学名为Diglyme,在CAS(国际化学文摘杂志)中编号为111-96-6,它的常见分子式是(CH3OCH2CH2)2O,分子量为134.17,常见熔点为mp -68°C,常见沸点为bp760 162°C,常见密度为d2020 0.0009451 g/cm3,这是一种由C 53.71%, H 10.52%, O 35.77%构成的化合物。
不含。
乙二醇二甲醚,主要用于聚合物化学、电化学、硼化学工艺领域,还用于树脂,硝化纤维素等溶剂。苯、联苯、三联苯、蒽等芳香烃在本品中与钠生成络合物,钠萘络合物在聚四氟乙烯等含氟树脂粘合时用于表面处理。同时,也用于汽油中卤素测定,而不是含有卤素。
乙二醇二甲醚,是一种有机化合物,分子式为C?H10O?,为无色透明液体,溶于水、乙醇、烃类,主要用于聚合物化学、电化学、硼化学工艺领域,还用作树脂、硝化纤维素等的溶剂以及医药抽提剂、有机合成中间体。
dme是乙二醇二甲醚。
dme也称作乙二醇二甲醚。乙二醇二甲醚,是一种有机物,分子式为C4H10O2,分子量为90.12,无色透明液体。熔点-58℃(-71℃),沸点84℃,相对密度0.8665(20/4℃),折光率1.3796,闪点0℃。能与水、醇混溶,溶于烃类溶剂。有强烈醚样气味。
乙二醇二甲醚的应用
乙二醇二甲醚为无色液体,有乙醚气味,性质稳定,能与水和乙醇、乙醚、氯仿等多种有机溶剂混溶。乙二醇二甲醚作为一种性能优良的非质子极性溶剂,除了用作气体吸收剂、萃取剂和脱漆剂外,还可用于电化学、硼化学、有机医药中间体合成等领域。
以上内容参考:百度百科-乙二醇二甲醚
编号 毒性类型 测试方法 测试对象 使用剂量 毒性作用 1 acute Oral Human 3380 mg/kg 1.胃肠道毒性Gastrointestinal - gastritis2.肝毒性Liver - other changes3.肾、输尿管和膀胱毒性Kidney, Ureter, Bladder -other changes 2 acute Inhalation Human 25 ppm 1.行为毒性Behavioral - tremor2.行为毒性Behavioral - convulsions or effect on seizure threshold3.行为毒性Behavioral - changes in motor activity (specific assay) 3 acute Oral Rodent - rat 2370 mg/kg 1.行为毒性Behavioral - altered sleep time (including change in righting reflex)2.肺部、胸部或者呼吸毒性Lungs, Thorax, or Respiration -other changes 4 acute Inhalation Rodent - rat 1500 ppm/7H 1.Details of toxic effects not reported other than lethal dose value 5 acute Intraperitoneal Rodent - rat 2500 mg/kg 1.Details of toxic effects not reported other than lethal dose value 6 acute Intravenous Rodent - rat 2068 mg/kg 1.血液毒性Blood - other hemolysis with or without anemia 7 acute Oral Rodent - mouse 2560 mg/kg 1.行为毒性Behavioral - somnolence (general depressed activity)2.行为毒性Behavioral - changes in motor activity (specific assay)3.心脏毒性Cardiac - other changes 8 acute Inhalation Rodent - mouse 1480 ppm/7H 1.行为毒性Behavioral - analgesia2.肺部、胸部或者呼吸毒性Lungs, Thorax, or Respiration -dyspnea3.肾、输尿管和膀胱毒性Kidney, Ureter, Bladder -hematuria 9 acute Intraperitoneal Rodent - mouse 2147 mg/kg 1.肾、输尿管和膀胱毒性Kidney, Ureter, Bladder -changes in both tubules and glomeruli2.血液毒性Blood - changes in spleen3.血液毒性Blood - other changes 10 acute Oral Rodent - rabbit 890 mg/kg 1.行为毒性Behavioral - general anesthetic2.血液毒性Blood - other hemolysis with or without anemia 11 acute Administration onto the skin Rodent - rabbit 1280 mg/kg 1.Details of toxic effects not reported other than lethal dose value 12 acute Oral Rodent - guinea pig 950 mg/kg 1.行为毒性Behavioral - general anesthetic2.胃肠道毒性Gastrointestinal - other changes3.肾、输尿管和膀胱毒性Kidney, Ureter, Bladder -other changes 13 MutipleDose Inhalation Rodent - rat 400 ppm/6H/2W-I 1.大脑毒性Brain and Coverings - other degenerative changes2.营养和代谢系统毒性Nutritional and Gross Metabolic - weight loss or decreased weight gain3.生化毒性Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - multiple enzyme effects 14 MutipleDose Oral Rodent - rat 10206 mg/kg/21D-C 1.内分泌毒性Endocrine - changes in thymus weight2.营养和代谢系统毒性Nutritional and Gross Metabolic - weight loss or decreased weight gain3.慢性病相关毒性Related to Chronic Data - changes in testicular weight 15 MutipleDose Oral Rodent - rat 500 mg/kg/10D-I 1.内分泌毒性Endocrine - changes in thymus weight2.免疫系统毒性Immunological Including Allergic - decreased immune response 16 MutipleDose Inhalation Rodent - rat 300 ppm/6H/13W-I 1.血液毒性Blood - changes in leukocyte (WBC) count2.营养和代谢系统毒性Nutritional and Gross Metabolic - weight loss or decreased weight gain3.慢性病相关毒性Related to Chronic Data - changes in testicular weight 17 MutipleDose Inhalation Rodent - rat 970 mg/m3/7H/5W-I 1.血液毒性Blood - changes in bone marrow (not otherwise specified)2.血液毒性Blood - changes in spleen 18 MutipleDose Inhalation Rodent - rat 1000 ppm/6H/11D-I 1.肾、输尿管和膀胱毒性Kidney, Ureter, Bladder -other changes in urine composition2.血液毒性Blood - changes in bone marrow (not otherwise specified)3.血液毒性Blood - changes in leukocyte (WBC) count 19 MutipleDose Administration onto the skin Rodent - rat 20 mg/kg/4W-I 1.血液毒性Blood - changes in other cell count (unspecified)2.血液毒性Blood - changes in leukocyte (WBC) count3.慢性病相关毒性Related to Chronic Data - changes in testicular weight 20 MutipleDose Intraperitoneal Rodent - rat 450 mg/kg/16D-I 1.血液毒性Blood - changes in other cell count (unspecified)2.生化毒性Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other Enzymes 21 MutipleDose Oral Rodent - rat 29484 mg/kg/13W-C 1.内分泌毒性Endocrine - changes in thymus weight2.血液毒性Blood - changes in platelet count3.营养和代谢系统毒性Nutritional and Gross Metabolic - weight loss or decreased weight gain 22 MutipleDose Administration onto the skin Rodent - rat 3200 mg/kg/4D-I 1.内分泌毒性Endocrine - changes in thymus weight2.免疫系统毒性Immunological Including Allergic - decrease in humoral immune response 23 MutipleDose Oral Rodent - mouse 12110 mg/kg/2W-C 1.内分泌毒性Endocrine - changes in thymus weight2.慢性病相关毒性Related to Chronic Data - changes in testicular weight 24 MutipleDose Oral Rodent - mouse 82 mg/kg/13W-C 1.内分泌毒性Endocrine - effect on menstrual cycle2.内分泌毒性Endocrine - other changes3.血液毒性Blood - changes in spleen 25 MutipleDose Inhalation Rodent - mouse 1000 ppm/6H/11D-I 1.血液毒性Blood - changes in leukocyte (WBC) count2.慢性病相关毒性Related to Chronic Data - changes in testicular weight 26 MutipleDose Inhalation Mammal - dog 750 ppm/7H/12W-I 1.血液毒性Blood - microcytosis with or without anemia2.血液毒性Blood - other changes 27 MutipleDose Inhalation Rodent - rabbit 300 ppm/6H/13W-I 1.内分泌毒性Endocrine - changes in thymus weight2.血液毒性Blood - changes in erythrocyte (RBC) count3.慢性病相关毒性Related to Chronic Data - changes in testicular weight 28 MutipleDose Administration onto the skin Rodent - guinea pig 65 mg/kg/13W-I 1.血液毒性Blood - changes in erythrocyte (RBC) count2.营养和代谢系统毒性Nutritional and Gross Metabolic - weight loss or decreased weight gain3.慢性病相关毒性Related to Chronic Data - changes in testicular weight 29 SkinEyeIrrition Administration onto the skin Rodent - rabbit 483 mg/24H 1.Mild 30 SkinEyeIrrition Administration into the eye Rodent - rabbit 97 mg 31 SkinEyeIrrition Administration into the eye Rodent - rabbit 500 mg/24H 1.Mild 32 SkinEyeIrrition Administration into the eye Rodent - guinea pig 10 ug 1.Mild 33 Mutation Human Lymphocyte 150 mmol/L 34 Mutation Oral Rodent - rat 500 mg/kg 35 Mutation Oral Rodent - rat 500 mg/kg 36 Mutation Oral Rodent - mouse 500 mg/kg 37 Reproductive Oral Rodent - rat 175 mg/kg,female 7-13 day(s) after conception 1.生殖毒性Reproductive - Specific Developmental Abnormalities -cardiovascular (circulatory) system 38 Reproductive Oral Rodent - rat 175 mg/kg,female 7-13 day(s) after conception 1.生殖毒性Reproductive - Maternal Effects - parturition2.生殖毒性Reproductive - Effects on Newborn -biochemical and metabolic 39 Reproductive Oral Rodent - rat 15015 mg/kg,male 13 week(s) pre-mating 1.生殖毒性Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, andcount) 40 Reproductive Oral Rodent - rat 100 mg/kg,male 1 day(s) pre-mating 1.生殖毒性Reproductive - Paternal Effects - testes, epididymis, spermduct 41 Reproductive Oral Rodent - rat 350 mg/kg,female 9-15 day(s) after conception 1.生殖毒性Reproductive - Fertility -litter size (e.g. # fetuses per littermeasured before birth)2.生殖毒性Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stuntedfetus)3.生殖毒性Reproductive - Specific Developmental Abnormalities -cardiovascular (circulatory) system 42 Reproductive Inhalation Rodent - rat 68 mg/kg/4H,female 1-19 day(s) after conception 1.生殖毒性Reproductive - Fertility -pre-implantation mortality (e.g. reduction in number of implants per femaletotal number of implants per corpora lutea)2.生殖毒性Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) 43 Reproductive Inhalation Rodent - rat 30 ppm/6H,male 65 day(s) pre-mating 1.生殖毒性Reproductive - Paternal Effects - testes, epididymis, spermduct 44 Reproductive Inhalation Rodent - rat 100 ppm/6H,female 6-17 day(s) after conception 1.生殖毒性Reproductive - Maternal Effects - parturition2.生殖毒性Reproductive - Fertility -female fertility index (e.g. # females pregnant per # sperm positive females# females pregnant per # femalesmated)3.生殖毒性Reproductive- Effects on Newborn -live birth index (measured after birth) 45 Reproductive Inhalation Rodent - rat 100 ppm/6H,female 6-17 day(s) after conception 1.生殖毒性Reproductive - Effects on Newborn -viability index (e.g., # alive at day 4 per # bornalive)2.生殖毒性Reproductive - Effects on Newborn -growth statistics (e.g.%, reduced weight gain) 46 Reproductive Inhalation Rodent - rat 30 ppm/6H,male 13 week(s) pre-mating 1.生殖毒性Reproductive - Fertility -post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) 47 Reproductive Administration onto the skin Rodent - rat 11592 mg/kg,female 6-17 day(s) after conception 1.生殖毒性Reproductive - Fertility -female fertility index (e.g. # females pregnant per # sperm positive females# females pregnant per # femalesmated)2.生殖毒性Reproductive - Effects on Embryo or Fetus - fetaldeath 48 Reproductive Administration onto the skin Rodent - rat 4375 mg/kg,male 7 day(s) pre-mating 1.生殖毒性Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, andcount)2.生殖毒性Reproductive - Paternal Effects - testes, epididymis, spermduct3.生殖毒性Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females) 49 Reproductive Administration onto the skin Rodent - rat 2 mg/kg,female 10 day(s) after conception 1.生殖毒性Reproductive - Fertility -post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) 50 Reproductive Administration onto the skin Rodent - rat 1 mg/kg,female 12 day(s) after conception 1.生殖毒性Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stuntedfetus)2.生殖毒性Reproductive - Specific Developmental Abnormalities -craniofacial (including nose andtongue)3.生殖毒性Reproductive - Specific Developmental Abnormalities -gastrointestinal system 51 Reproductive Intraperitoneal Rodent - rat 330 mg/kg,female 12 day(s) after conception 1.生殖毒性Reproductive - Specific Developmental Abnormalities -musculoskeletal system2.生殖毒性Reproductive - Specific Developmental Abnormalities -cardiovascular (circulatory) system 52 Reproductive Intraperitoneal Rodent - rat 190 mg/kg,female 14 day(s) after conception 1.生殖毒性Reproductive - Specific Developmental Abnormalities -Central Nervous System2.生殖毒性Reproductive - Specific Developmental Abnormalities -urogenital system 53 Reproductive Intraperitoneal Rodent - rat 190 mg/kg,female 12 day(s) after conception 1.生殖毒性Reproductive - Specific Developmental Abnormalities -musculoskeletal system 54 Reproductive Intraperitoneal Rodent - rat 190 mg/kg,female 8 day(s) after conception 1.生殖毒性Reproductive - Fertility -post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) 55 Reproductive Subcutaneous Rodent - rat 600 mg/kg,female 6-20 day(s) after conception 1.生殖毒性Reproductive- Effects on Newborn -live birth index (measured after birth)2.生殖毒性Reproductive - Effects on Newborn -viability index (e.g., # alive at day 4 per # bornalive) 56 Reproductive Subcutaneous Rodent - rat 440 mg/kg,female 7-17 day(s) after conception 1.生殖毒性Reproductive- Effects on Newborn -live birth index (measured after birth) 57 Reproductive Oral Rodent - rat 250 mg/kg,female 13 day(s) after conception 1.生殖毒性Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stuntedfetus)2.生殖毒性Reproductive - Specific Developmental Abnormalities -musculoskeletal system 58 Reproductive Oral Rodent - mouse 175 mg/kg,female 11 day(s) after conception 1.生殖毒性Reproductive - Specific Developmental Abnormalities -musculoskeletal system 59 Reproductive Oral Rodent - mouse 2 mg/kg,female 7-14 day(s) after conception 1.生殖毒性Reproductive - Fertility -litter size (e.g. # fetuses per littermeasured before birth)2.生殖毒性Reproductive - Effects on Embryo or Fetus - fetaldeath3.生殖毒性Reproductive - Specific Developmental Abnormalities -Central Nervous System 60 Reproductive Oral Rodent - mouse 500 mg/kg,female 9 day(s) after conception 1.生殖毒性Reproductive - Fertility -post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)2.生殖毒性Reproductive - Fertility - litter size (e.g. # fetuses per littermeasured before birth)3.生殖毒性Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stuntedfetus) 61 Reproductive Oral Rodent - mouse 250 mg/kg,female 11 day(s) after conception 1.生殖毒性Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stuntedfetus)2.生殖毒性Reproductive - Specific Developmental Abnormalities -musculoskeletal system 62 Reproductive Oral Rodent - mouse 6250 mg/kg,male 25 day(s) pre-mating 1.生殖毒性Reproductive - Paternal Effects - testes, epididymis, spermduct 63 Reproductive Inhalation Rodent - mouse 1000 ppm/6H,male 11 day(s) pre-mating 1.生殖毒性Reproductive - Paternal Effects - testes, epididymis, spermduct 64 Reproductive Inhalation Rodent - mouse 500 ppm/7H,male 5 day(s) pre-mating 1.生殖毒性Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, andcount) 65 Reproductive Inhalation Rodent - mouse 50 ppm/6H,female 6-15 day(s) after conception 1.生殖毒性Reproductive - Fertility -litter size (e.g. # fetuses per littermeasured before birth)2.生殖毒性Reproductive - Specific Developmental Abnormalities -urogenital system 66 Reproductive Inhalation Rodent - mouse 50 ppm/6H,female 6-15 day(s) after conception 1.生殖毒性Reproductive - Specific Developmental Abnormalities -musculoskeletal system2.生殖毒性Reproductive - Specific Developmental Abnormalities -urogenital system 67 Reproductive Subcutaneous Rodent - mouse 1200 mg/kg,female 7-13 day(s) after conception 1.生殖毒性Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stuntedfetus) 68 Reproductive Subcutaneous Rodent - mouse 3200 mg/kg,female 7-14 day(s) after conception 1.生殖毒性Reproductive - Fertility -post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) 69 Reproductive Subcutaneous Rodent - mouse 250 mg/kg,female 8 day(s) after conception 1.生殖毒性Reproductive - Specific Developmental Abnormalities -Central Nervous System2.生殖毒性Reproductive - Specific Developmental Abnormalities -craniofacial (including nose andtongue) 70 Reproductive Intravenous Rodent - mouse 250 mg/kg,female 8 day(s) after conception 1.生殖毒性Reproductive - Specific Developmental Abnormalities -Central Nervous System 71 Reproductive Oral Primate - monkey 930 mg/kg,female 20-45 day(s) after conception 1.生殖毒性Reproductive - Fertility -abortion2.生殖毒性Reproductive - Effects on Embryo or Fetus - fetaldeath 72 Reproductive Oral Primate - monkey 633 mg/kg,female 20-45 day(s) after conception 1.生殖毒性Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stuntedfetus) 73 Reproductive Inhalation Rodent - rabbit 300 ppm/6H,male 65 day(s) pre-mating 1.生殖毒性Reproductive - Paternal Effects - testes, epididymis, spermduct 74 Reproductive Inhalation Rodent - rabbit 50 ppm/6H,female 6-18 day(s) after conception 1.生殖毒性Reproductive - Specific Developmental Abnormalities -body wall2.生殖毒性Reproductive - Specific Developmental Abnormalities -cardiovascular (circulatory) system3.生殖毒性Reproductive - Specific Developmental Abnormalities -urogenital system 75 Reproductive Inhalation Rodent - rabbit 50 ppm/6H,female 6-18 day(s) after conception 1.生殖毒性Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stuntedfetus)2.生殖毒性Reproductive - Specific Developmental Abnormalities -body wall3.生殖毒性Reproductive - Specific Developmental Abnormalities -musculoskeletal system 76 Reproductive Inhalation Rodent - rabbit 10 ppm/6H,female 6-18 day(s) after conception 1.生殖毒性Reproductive - Fertility -post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)2.生殖毒性Reproductive - Specific Developmental Abnormalities -musculoskeletal system 77 Reproductive Oral Rodent - guinea pig 6250 mg/kg,male 25 day(s) pre-mating 1.生殖毒性Reproductive - Paternal Effects - testes, epididymis, spermduct 78 Reproductive Administration onto the skin Rodent - guinea pig 65 mg/kg,male 65 day(s) pre-mating 1.生殖毒性Reproductive - Paternal Effects - testes, epididymis, spermduct 79 Reproductive Oral Rodent - hamster 1562 mg/kg,male 25 day(s) pre-mating 1.生殖毒性Reproductive - Paternal Effects - testes, epididymis, spermduct
迅速撤离泄漏污染区人员至安全区,并进行隔离,严格限制出入。切断火源。建议应急处理人员戴自给正压式呼吸器,穿消防防护服。尽可能切断泄漏源,防止进入下水道、排洪沟等限制性空间。小量泄漏:用活性炭或其它惰性材料吸收。也可以用大量水冲洗,洗水稀释后放入废水系统。大量泄漏:构筑围堤或挖坑收容;用泡沫覆盖,降低蒸气灾害。用防爆泵转移至槽车或专用收集器内,回收或运至废物处理场所处置。
呼吸系统防护:高浓度蒸气接触可佩戴过滤式防毒面具(半面罩)。
眼睛防护:一般不需要特殊防护,高浓度接触时可戴化学安全防护眼镜。
身体防护:穿防静电工作服。
手防护:戴乳白色胶手套。
其它:工作现场禁止吸烟、进食和饮水。工作毕,淋浴更衣。注意个人清洁卫生。 皮肤接触:脱去被污染的衣着,用肥皂水和清水彻底冲洗皮肤。
眼睛接触:提起眼睑,用流动清水或生理盐水冲洗。就医。
吸入:迅速脱离现场至空气新鲜处。保持呼吸道通畅。如呼吸困难,给输氧。如呼吸停止,立即进行人工呼吸。就医。
食入:饮足量温水,催吐,就医。
灭火方法:尽可能将容器从火场移至空旷处。喷水保持火场容器冷却,直至灭火结束。处在火场中的容器若已变色或从安全泄压装置中产生声音,必须马上撤离。灭火剂:抗溶性泡沫、干粉、二氧化碳、砂土。